BPSA Publishes Two New Papers Highlighting the Role of Single-Use Technologies in Cell & Gene Therapy and Continuous Bioprocessing
April 20, 2026
The Bio-Process Systems Alliance (BPSA) is pleased to announce the publication of two new technical papers focused on advancing the implementation of single-use technologies across biopharmaceutical manufacturing. The new resources address manufacturing bottlenecks in cell and gene therapy production and the growing adoption of continuous bioprocessing.
The first paper, Navigating Cell and Gene Therapy Manufacturing Bottlenecks, examines common constraints that impact the scalability and reliability of cell and gene therapy manufacturing. The paper highlights how single-use technologies address operational bottlenecks and support flexible and efficient manufacturing strategies in this rapidly evolving sector.
The second paper, Continuous Bioprocessing with Single-Use Technologies, explores how single-use systems support the transition from traditional batch processing to continuous manufacturing. This paper provides a practical overview of key considerations, challenges, and opportunities for integrating single-use technologies into continuous operations.
“These two papers focus on areas that are at the center of innovation and growth across bioprocessing,” said BPSA Chair, Mark Petrich, PhD, of Krystal Biotech. “Single-use technologies continue to play a critical role both in addressing the unique challenges of cell and gene therapy manufacturing and in enabling more flexible approaches to continuous bioprocessing. These BPSA papers provide valuable insights for single-use suppliers and end-users alike.”
“I would like to thank the BPSA Advanced Therapies Committee, co-chaired by Brendan Lucey of Kivi Bio LLC and Todd Pangburn, PhD of Dupont, and the BPSA Continuous Bioprocessing Committee, co-chaired by David Chau, PhD of Thermo Fisher Scientific and Davinder Chawla, PhD, of Sanofi, for their dedication and contributions.”
The papers are now available for download:
Navigating Cell and Gene Therapy Manufacturing Bottlenecks – Download
Continuous Bioprocessing with Single-Use Technologies – Download
Visit BPSA’s resource library for additional information.
Special thanks to BPSA sustaining sponsors: AdvantaPure, Burkert Fluid Control Systems, Cytiva, CPC Biotech, Entegris, MilliporeSigma, PendoTECH, Renolit Healthcare, Saint-Gobain Life Sciences, Sartorius and Solvias for making these resources possible.